A simple and flavorful slow cooker Mississippi pot roast made with chuck roast, ranch seasoning, au jus mix, butter, and pepperoncini peppers. Perfect for easy weeknight dinners with melt-in-your-mouth tenderness and a tangy, buttery sauce.
Searing the roast is optional but adds extra flavor. Use the pepperoncini juice for signature tang. For a thicker sauce, use cornstarch slurry at the end. Butter keeps the roast juicy; substitute with olive oil or plant-based butter for dairy-free. Leftover sauce is great for sandwiches or mashed potatoes. Slow and low cooking yields best tenderness.
Keywords: Mississippi pot roast, slow cooker pot roast, pepperoncini pot roast, easy pot roast recipe, weeknight dinner, crockpot roast